PFKFB3 DEPRIVATION ATTENUATES THE CISPLATIN RESISTANCE VIA BLOCKING ITS AUTOPHAGIC ELIMINATION IN COLORECTAL CANCER CELLS

PFKFB3 deprivation attenuates the cisplatin resistance via blocking its autophagic elimination in colorectal cancer cells

Introduction6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 (PFKFB3) is highly expressed in several cancers and TROUSERS URBAN COTTON plays important roles during the whole pathological process of cancer.It is also involved in chemoresistance, while the intrinsic mechanism needs to be further revealed.MethodsThe different responses t

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Xanthopygoides niger Cameron, 1951 (Xanthopygina) belongs to the genus Philonthus Stephens, 1829 (Philonthina): systematic and nomenclatural changes for the African Staphylinini (Coleoptera, Staphylinidae, Staphylininae, Staphylinini)

A poorly known African species Xanthopygoides niger (Cameron, 1951), hitherto a member of the monotypic Battery Testers genus of the subtribe Xanthopygina is transferred to the subgenus Raucalius Tottenham, 1949 of the genus Philonthus Stephens, 1829, subtribe Philonthina, and redescribed.The new genus-group synonym Raucalius Tottenham, 1951 = Xant

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In-service fatigue cracking of the propeller shafts joined by a spline-pinned construction to the engines of AN-24, AN-26, and IL-18 aircrafts

The paper delivers a Loaf Tin critical review of the research data on the crack initiation and crack growth patterns characteristic of the components of the spline-bolted joints between the propeller shaft and reducer shaft at An-24, An-26, and Il-18 aircrafts.Cracks in the shafts nucleated because of reduced bolt-fastening force.Actually, the bolt

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Neoxabea mexicana sp. nov. (Gryllidae: Oecanthinae): A new species from Mexico and a key for Neoxabea in North and Central America

A new species of tree cricket, Neoxabea mexicana sp.nov., is described from northeast Mexico.Although it has morphological similarities to two other species found in Mexico, there are distinguishing characters, such as a well-developed tubercle on the Travel Cups pedicel, black markings on the maxillary palpi, one of the two pairs of spots on the f

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Ethanol and High-Value Terpene Co-Production from Lignocellulosic Biomass of Cymbopogon flexuosus and Cymbopogon martinii.

Cymbopogon flexuosus, lemongrass, and C.martinii, palmarosa, are perennial grasses grown to produce essential oils for the fragrance industry.The objectives of this study were (1) to evaluate biomass and oil yields as a function of nitrogen and sulfur fertilization, and (2) to characterize their utility for lignocellulosic ethanol compared to Panic

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