PFKFB3 deprivation attenuates the cisplatin resistance via blocking its autophagic elimination in colorectal cancer cells
Introduction6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 (PFKFB3) is highly expressed in several cancers and TROUSERS URBAN COTTON plays important roles during the whole pathological process of cancer.It is also involved in chemoresistance, while the intrinsic mechanism needs to be further revealed.MethodsThe different responses t